Metal-mediated synthesis of furans and pyrroles
نویسندگان
چکیده
منابع مشابه
Assisted tandem catalytic RCM-aromatization in the synthesis of pyrroles and furans.
An assisted tandem catalytic transformation of diallyl amines and diallyl ethers into N-aryl pyrroles and furans, respectively, is described. The sequence relies on ring closing metathesis followed by dehydrogenation of the initially formed dihydropyrroles and dihydrofurans. Both steps are Ru-catalyzed, but the sequence requires only one precatalyst, because conversion of the metathesis catalys...
متن کاملDesign of novel multicomponent cycloadditions using conjugated furans and pyrroles
Research in the Herndon group focuses on the discovery of new organotransition metal-based processes for use in organic synthesis. Of specific interest are reactions that transform simple starting materials into complex products in a general, predictable, efficient, and stereoselective manner. Most of our present activity involves exploration of the coupling reaction between Fischer carbene com...
متن کاملsynthesis of sulfides from alcohols and thiols in solvent-freeconditions and deoxygenation of sulfoxides
کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...
15 صفحه اولA new facile approach to the synthesis of 3-methylthio-substituted furans, pyrroles, thiophenes, and related derivatives.
2-(methylthio)-1,4-diaryl-2-butene-1,4-dione (3) are prepared from readily available aryl methyl ketones in the presence of copper(II) oxide, iodine, and dimethyl sulfoxide. The success of the cross-coupling reaction of 4-chloroacetophenone with 2-acetylthiophene confirms a proposed self-sorting tandem reaction mechanism. Both Z- and E-isomers of compound 3 are readily converted into the corres...
متن کاملRegiodivergent heterocyclization: a strategy for the synthesis of substituted pyrroles and furans using α-formyl ketene dithioacetals as common precursors.
The selective construction of a diverse array of five-membered aromatic heterocycles from common starting materials is an attractive and challenging task. We report here that 5-alkylthio-pyrroles, 4-alkylthiocarbonyl-pyrroles and 2-alkylthio-4-tosyl-furans can be prepared, selectively, in a single operation using the readily available α-formyl ketene dithioacetals as common precursors, through ...
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ژورنال
عنوان ژورنال: Arkivoc
سال: 2007
ISSN: 1551-7012
DOI: 10.3998/ark.5550190.0008.a11